If you need to buy TB-500 in Canada for a lab that goes through vials by the case rather than one at a time, the first job is confirming which molecule the order actually contains. The name “TB-500” is attached to two different materials, one of them more than five times heavier than the other, and a single line on the mass spectrum tells them apart. Below: that identity check, the other figures on the report worth reading before a lot is accepted, and how Bulk Peptides supplies TB-500 in bulk to Canadian labs.
Buy TB-500 in Canada by volume: how ordering works
Our quantity breaks are mix-and-match: every vial in the cart counts toward the tier, TB-500 or otherwise. Two or three vials take 5% off, four to six take 15%, seven to nine take 25%, and ten or more take 35%. Orders beyond a few cases can be quoted individually — the bulk pricing page explains how to ask.
Shipping is domestic only, to Canadian addresses, so nothing crosses a border and there is no customs, duty or brokerage to clear. At checkout you pick the carrier and speed: Canada Post, FedEx, Purolator or UPS, each in regular or express. We dispatch within one business day, transit usually takes two to five days, and orders above $200 CAD travel free. Payment is by e-Transfer, USDT or selected crypto.
Two molecules share one name
Thymosin β4 is a full protein: 43 residues, N-terminal acetylation, a mass close to 4,963 Da. The product normally labelled TB-500 is something far smaller — a synthetic fragment taken from the protein’s actin-binding stretch, typically the acetylated seven-residue sequence Ac-LKKTETQ, weighing in at around 889 Da.
These are not two grades of one substance, and secondary sources quoting “TB-500” results seldom say which of the two the underlying paper used. Our explainer on why the TB-500 fragment and thymosin β4 should not be conflated shows how to read that literature carefully.
Confirming identity from the report
Find the measured mass. A value near 889 Da means the heptapeptide; a value near 4,963 Da means the full-length protein. The gap is enormous, so resolution is not a concern — whatever instrument generated the report can separate them easily.
A report with no measured mass, or with a measured value but no calculated figure beside it, leaves the most basic question open. When a vendor cannot name the sequence in the vial, that tells a procurement lead what they need to know about the vendor.
Reading the HPLC number properly
An HPLC purity result is the main peak’s area expressed as a share of all the area the detector picked up. Whether that share tells you much depends on two things.
Wavelength comes first, and it is printed on the trace. Run at 214 or 220 nm, the detector responds to the peptide backbone, so every peptide-like impurity shows up. Run at 280 nm, it sees only aromatic side chains — tryptophan, tyrosine and, faintly, phenylalanine — and Ac-LKKTETQ has none of them. On this sequence a 280 nm figure says almost nothing, since the fragment and most of its contaminants barely register. For QC staff, that wavelength is the most important line on the page and the one most often overlooked.
Length is the second factor. Losing one residue from a seven-residue chain is a proportionally bigger change than losing one from a 43-mer, so deletion products pull away from the main peak more cleanly. A purity value on a short peptide therefore tends to carry more information, not less. See how deletion, truncation and oxidation impurities appear, and our guide to interpreting a peptide HPLC trace for what a shoulder beside the main peak suggests.
Cost per mg at volume: what the milligram includes
When you compare cost per milligram across a large order, remember the label states total solid: the peptide, its counter-ion and leftover moisture. With two lysine residues in the sequence, the salt makes a genuine contribution to that weight; our note on acetate versus TFA salt forms covers the difference. Moisture is determined by Karl Fischer titration and often runs at a few percent — explained in measuring water in freeze-dried peptide.
The number that corrects for both is net peptide content, and it rarely appears on a report. Our net peptide content guide walks through how the same vial can honestly read 98% pure and 78% peptide.
The BPC-157 and TB-500 blend
TB-500 is often sold pre-combined with BPC-157. A two-component vial raises an issue a single-compound vial never does: a purity percentage summarises one chromatogram, and a trace containing two deliberate components cannot be read like a trace containing one. What a blend report should give you is separate identity confirmation for each peptide and a stated ratio, not a single headline number.
Our guide to composition and purity in multi-peptide blend vials lists what to request, and what the BPC-157 literature can and cannot support addresses the partner compound.
Receiving and storing a multi-vial lot
Freeze-dried peptide pulls moisture from the air, and a cold vial opened straight from storage will fog with condensation. Let each vial warm to room temperature first, recap it quickly and store it away from light. For the chemistry, read how light, oxygen and heat degrade peptides; for the creeping balance reading, see weighing hygroscopic lyophilised material. If one vial will be accessed many times, our aliquoting notes cover keeping exposure down.
Testing, certificates and their limits
Our products are third-party tested by HPLC and purity analysis, and certificates are published for some products on the COA page, shown exactly as the lab issued them. No paperwork is packed with the shipment; when logging a delivery, match each vial to its report using the cap and crimp colour pictured on that report.
An identity and purity report does not address sterility, endotoxin, or fitness for use in people or animals — those would be separate assays, and they were not performed. Read what “research grade” excludes, plus how in-house and third-party testing differ and why the person choosing the sample affects what a report proves.
TB-500 vial sizes
- TB-500 5 mg — suits method development, where a vial gets opened often.
- TB-500 10 mg — the lower cost per milligram once your working amount is fixed.
- BPC-157 & TB-500 blend 10 mg — two peptides in a single vial; the blend notes above apply.
Every product is sold strictly for laboratory research. It is not a medicine or a supplement, and it must not be used in humans or animals.
