Description
A 20 mg vial of MOTS-c is aimed at groups running it through weeks of culture work, where one consistent supply is worth more than a smaller upfront order.
MOTS-c 20 mg for sustained programmes
Because MOTS-c oxidises easily, the way a larger vial is handled matters more than the size itself. The usual approach is to dissolve the whole vial once, under clean conditions, and divide it immediately into single-use portions that are frozen and never re-thawed. That keeps every experiment in the series drawing from material with the same history.
On HPLC the peptide is strongly retained for its size because of its aromatic residues, so a gradient that suits shorter peptides may need extending. The identity table gives the formula C101H152N28O22S2 for checking mass-based methods run in your own lab.
Compound identity and specification
| Compound | MOTS-c |
|---|---|
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular formula | C101H152N28O22S2 |
| Molecular mass | 2174.6 g/mol |
| CAS registry number | 1627580-64-6 |
| PubChem | CID 146675088 |
| Vial content | 20 mg |
| Physical form | Lyophilised powder in a sealed vial |
| Analysis | Third-party HPLC and purity testing to a 99%+ specification; certificates are posted on our COAs page |
| Supplied for | Laboratory research use only |
Questions about MOTS-c 20mg
Is it worth dividing a 20 mg vial on day one?
Yes. Single-use portions avoid repeated thawing and exposure to air, both of which accelerate oxidation.
Do quantity breaks apply to MOTS-c 20 mg?
Yes. Ten or more vials in the cart, in any mix, take 35% off each, with smaller breaks from two vials.
Where are certificates posted?
On our COAs page, matched to vials by cap and crimp colour.
Research literature
- Lee C, et al. Cell Metab. 2015;21(3):443-454. In mouse skeletal muscle and cultured cells, measured inhibition of the folate-methionine cycle and de novo purine biosynthesis with consequent AMPK activation. Source · PMID 25738459
- Kim KH, et al. Cell Metab. 2018;28(3):516-524. In cultured human cells under receptor-signalling stress, measured AMPK-dependent nuclear translocation and occupancy at antioxidant-response-element genes. Source · PMID 29983246
- Reynolds JC, et al. Nat Commun. 2021;12:470. In young, middle-aged and old CD-1 and C57BL/6 mice, measured running capacity, grip strength, gait and skeletal-muscle transcriptomic profiles. Source · PMID 33473109
Certificates for our compounds are posted on the certificates of analysis page and matched to vials by cap and crimp colour. If the one for this product is not up yet, contact the order desk.
Related research compounds
Mitochondrial & Cellular Compounds
research peptide catalogue
Supplied for laboratory research use only. Not for human or veterinary use.
