Description
Add the glucagon receptor to the two incretin receptors and you have three related class B GPCRs. A triple agonist lets a lab study all three from a single molecule.
GLP-3 10 mg, a three-receptor agonist
The glucagon receptor, GCGR, shares its overall architecture with GLP-1R and GIPR, and all three couple to Gs and cAMP. What differs is where each is expressed and how strongly each responds to a given agonist. A triple agonist’s value as a research tool lies in that balance, which has to be measured rather than assumed.
The 10 mg fill is the practical starting point: enough to build a method, confirm activity at each receptor and decide whether the programme needs a larger vial or a case pack.
Receptor profile and specification
| Compound class | Triple GLP-1, GIP and glucagon receptor agonist peptide |
|---|---|
| Target receptors | GLP-1R, GIPR and GCGR (class B GPCRs) |
| Primary functional readout | Gs-coupled cAMP accumulation in receptor-expressing cells |
| Vial content | 10 mg |
| Physical form | Lyophilised powder in a sealed vial |
| Analysis | Third-party HPLC and purity testing to a 99%+ specification; certificates are posted on our COAs page |
| Supplied for | Laboratory research use only |
Questions about GLP-3 10mg
Which three receptors are involved?
The GLP-1 receptor, the GIP receptor and the glucagon receptor (GCGR).
Do all three receptors signal the same way?
All three couple mainly to Gs and raise cAMP, but their potency for a given agonist differs.
Is there a discount for buying several vials?
Yes. Volume pricing applies automatically in the cart: 5% off at two vials, rising to 35% off at ten or more vials in the cart, mixed across any products.
Certificates for our compounds are posted on the certificates of analysis page and matched to vials by cap and crimp colour. If the one for this product is not up yet, contact the order desk.
Related research compounds
Browse more compounds in Incretin & Glucagon Peptides, or view the full research peptide catalogue.
Supplied for laboratory research use only. Not for human or veterinary use.
