Description
This blend combines a growth-hormone-releasing hormone analogue with a ghrelin-receptor agonist. The two act on different receptors, which is exactly why they are so often studied together.
Two receptors, one vial
CJC-1295 without DAC is Mod GRF(1-29), a 29-residue peptide that binds the GHRH receptor. Ipamorelin is a pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2, that binds the growth hormone secretagogue receptor GHS-R1a. Their sizes differ by almost five-fold, so the blend separates cleanly into two peaks on reversed-phase HPLC, with ipamorelin eluting well before the larger GHRH analogue.
Pre-combining the pair saves time in labs that always use them together, for example when comparing single-receptor and dual-receptor stimulation in pituitary cell models. Where the ratio needs to change between experiments, the separate CJC-1295 and ipamorelin vials give that control.
Compound identity and specification
| Component | Sequence | Formula | Mass (g/mol) | CAS |
|---|---|---|---|---|
| CJC-1295 without DAC (Mod GRF 1-29) CID 56841945 | [D-Ala2, Gln8, Ala15, Leu27]-GRF(1-29) amide | C152H252N44O42 | 3367.9 | 863288-34-0 |
| Ipamorelin CID 9831659 | Aib-His-D-2-Nal-D-Phe-Lys-NH2 | C38H49N9O5 | 711.9 | 170851-70-4 |
Questions about CJC-1295 & Ipamorelin Blend 10mg
Which peptides are in the blend?
CJC-1295 without DAC (Mod GRF 1-29) and ipamorelin, with both listed in the identity table below.
How do I verify a two-peptide vial?
Expect two main peaks by HPLC. Each is assessed separately against the specification.
Can I get the components separately?
Yes. CJC-1295 without DAC is stocked at 5 mg and ipamorelin at 5 mg and 10 mg.
Research literature
- Jette L, et al. Endocrinology. 2005;146(7):3052-3058. In cultured rat anterior pituitary cells and Sprague-Dawley rats, measured GH secretion, Cys34-albumin conjugate formation and resistance to DPP-IV cleavage. Source · PMID 15817669
- Alba M, et al. Am J Physiol Endocrinol Metab. 2006;291(6):E1290-E1294. In GHRH-knockout mice, measured pituitary GH and IGF-I expression. Source · PMID 16822960
- Raun K, et al. Eur J Endocrinol. 1998;139(5):552-561. In primary rat pituitary cell culture, anaesthetised rats and conscious swine, measured GH release and the absence of concomitant ACTH and cortisol elevation. Source · PMID 9849822
- Johansen PB, et al. Growth Horm IGF Res. 1999;9(2):106-113. In rats, measured longitudinal bone growth following administration. Source · PMID 10373343
- Svensson J, et al. J Endocrinol. 2000;165(3):569-577. In adult female rats, characterised the response to chronic secretagogue exposure; see the linked record for endpoints. Source · PMID 10828840
Certificates for our compounds are posted on the certificates of analysis page and matched to vials by cap and crimp colour. If the one for this product is not up yet, contact the order desk.
Related research compounds
GHS
research peptide catalogue
Supplied for laboratory research use only. Not for human or veterinary use.
