Description
Selank starts from tuftsin, a four-residue peptide cleaved from immunoglobulin G, and extends it with the same Pro-Gly-Pro tripeptide that appears in Semax.
Selank 10 mg, tuftsin with a stabilising tail
The full sequence TKPRPGP has a mass of 751.9 g/mol and two basic residues, lysine and arginine, that make it strongly cationic at neutral pH. Three prolines in seven positions give it a rigid backbone and good resistance to many peptidases. It lacks methionine and tryptophan, so it is less prone to oxidation than Semax.
Research has mostly been carried out in rodent behavioural models and in studies of gene expression in cultured cells. The 10 mg format is the one to choose for longer series; the 5 mg vial suits a first look.
Compound identity and specification
| Compound | Selank |
|---|---|
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP) |
| Molecular formula | C33H57N11O9 |
| Molecular mass | 751.9 g/mol |
| CAS registry number | 129954-34-3 |
| PubChem | CID 11765600 |
| Vial content | 10 mg |
| Physical form | Lyophilised powder in a sealed vial |
| Analysis | Third-party HPLC and purity testing to a 99%+ specification; certificates are posted on our COAs page |
| Supplied for | Laboratory research use only |
Questions about Selank 10mg
What is tuftsin?
A tetrapeptide, Thr-Lys-Pro-Arg, released from the Fc region of immunoglobulin G. Selank adds Pro-Gly-Pro to it.
Is Selank prone to oxidation?
Less than many peptides, because it contains no methionine, cysteine or tryptophan.
Is a smaller vial available?
Yes, 5 mg.
Research literature
Peer-reviewed studies involving this compound and its class. All findings listed are from in vitro, cell culture or animal models and are provided for scientific reference only. This product is supplied for laboratory research and is not approved for human consumption, clinical, or veterinary use.
- Semenova TP, et al. Eksp Klin Farmakol. 2009;72(4):6-8. In male Wistar rats pretreated with the serotonin synthesis inhibitor PCPA, measured serotonin turnover in brainstem and neocortex. Source · PMID 19803361
- Kolomin T, et al. Regul Pept. 2011;170(1-3):18-23. In mouse spleen, measured expression of inflammation-related genes following administration. Source · PMID 21609736
- Volkova A, et al. Front Pharmacol. 2016;7:31. In rat frontal cortex, measured expression of 84 GABAergic and neurotransmission-related genes 1-3 hours after administration, against diazepam. Source · PMID 26924987
Certificates for our compounds are posted on the certificates of analysis page and matched to vials by cap and crimp colour. If the one for this product is not up yet, contact the order desk.
Related research compounds
Browse more compounds in Neuropeptides, or view the full research peptide catalogue.
Supplied for laboratory research use only. Not for human or veterinary use.
